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Cat No | BIOP2381 |
Conjugate | |
Type | 免疫检查点 |
Source | Mammalian |
Tag | His-Avi |
Size | 100 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS, pH 7.4. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | BTLA1;CD272 |
Purification | > 95% by SDS-PAGE. |
MolecularWeight | |
Description | |
Background | B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 . BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. |