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Cat No | BIOP2380 |
Conjugate | |
Type | 免疫检查点 |
Source | Mammalian |
Tag | His |
Size | 100 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS, pH 7.4. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | IAP;MER6;OA3 |
Purification | > 95% by SDS-PAGE. |
MolecularWeight | |
Description | |
Background | CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a dont eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers. |