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重组蛋白

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Recombinant Mouse SCF protein,His

Cat NoADMD-103
Conjugate
Type重组蛋白
SourceHEK293
TagHis
Size1mg
ApplicationImmunology
FormatLiquid
Purity>95 %, SDS-PAGE
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS
SpeciesMouse
StorageStore at -20 degree. Avoid repeated freeze/thaw cycles.
SynonymsFPH2, FPHH, KIT ligand, Kitl, KITLG, KL-1, MGF, SCF, SF, SHEP7, SLF
PurificationProtein A/G
NoteFor research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals.
MolecularWeight22.3 kDa
Description
BackgroundSCF(Stem cell factor) also known as mast cell growth factorang kit ligand, is a hematopoietic growth factor. It plays an role in hematopoiesis (formation of blood cells), spermatogenesis, and melanogenesis. SCF is expressed in where hematopoiesis takes place, such as the fetal liver and bone marrow. SCF binding to c-kit ligand(CD117)causes the receptor to homodimerize and auto-phosphorylate at tyrosine residues. SCF and c-kit ligand are up-regulated in human malignancies including gastrointestinal stromal tumor, breast cancer, hematopoietic cell, myeloid leukaemia, and glioma. The SCF/c-kit pathway also plays a rolein the regulation of cell survival and proliferation, stem cell maintenance, mast cell development, migration.SCF and c-kit were confirmed as key role in hematopoietic function in adult mice.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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