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Recombinant Human VEGFR2/KDR protein,Fc

Cat NoADMD-090
Conjugate
Type重组蛋白
SourceHEK293
TagFc
Size1mg
ApplicationImmunology
FormatLiquid
Purity>95 %, SDS-PAGE
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS
SpeciesHuman
StorageStore at -20 degree. Avoid repeated freeze/thaw cycles.
SynonymsCD309, FLK1, Flk-1, KDR, KRD1, VEGFR, VEGFR2
PurificationProtein A/G
NoteFor research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals.
MolecularWeight110.3 kDa
Description
BackgroundVEGFR2, also named as KDR, FLK1 and CD309, is one of the two tyrosine kinase receptors involved in angiogenesis. VEGFR2 is mainly distributed in vascular endothelial cells, lymphatic endothelial cells, and embryonic precursor cells, and can bind to VEGF-A, VEGF-C, and VEGF-D. When activated by its ligand VEGF, VEGFR2 promotes neighbouring vessel formation to facilitate the delivery of growth factors, nutrients and oxygen for cancer proliferation, migration, metastasis and survival. VEGF and VEGFR2 mediated angiogenesis contributes to the aggressive natures and leads to high mortality rate in gastric cancer.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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