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Recombinant Human FGFR3(IIIb) protein,Fc,Myc,His

Cat NoADMD-066
Conjugate
Type重组蛋白
SourceHEK293
TagFc,Myc,His
Size1mg
ApplicationImmunology
FormatLiquid
Purity>90 %, SDS-PAGE
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS
SpeciesHuman
StorageStore at -20 degree. Avoid repeated freeze/thaw cycles.
SynonymsACH, CD333, CEK2, FGFR3, FGFR3 (IIIb), HSFGFR3EX, JTK4
PurificationProtein A/G
NoteFor research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals.
MolecularWeight67.1 kDa
Description
BackgroundFGFR3 (Fibroblast growth factor receptor 3) is a tyrosine-protein kinase that that acts as cell-surface receptor for fibroblast growth factors. FGFR3 binds acidic and basic fibroblast GH and plays important roles in development, osteogenesis, and bone maintenance. FGFR3 is highly expressed in chondrocytes and osteoblasts, and germline mutations are associated with bone growth disorders such as achondroplasia, chondrodysplasia, and thanatophoric dysplasia. Due to frequent mutations in certain cancers, FGFR3 gene has also been associated with tumor progression.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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