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Mouse Anti-Human CD45RO Antibody(Clone UCHL1), BOT Fluor 647

Cat NoBIOS-2624F
Conjugate
Type流式抗体
CloneUCHL1
SourceMouse
TagBOT Fluor 647
Size1 mg
ApplicationFCM
FormatLiquid
Purity>90%
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS; pH 7.4.
StorageStore at -20 degree for long term.
SynonymsCD45RO;UCHL1;泛素羧基末端酯酶L1
PurificationSDS-PAGE
MolecularWeight
Description
BackgroundCD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
We can provide a variety of products such as diagnostic proteins; target proteins; cytokines; etc.
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