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Armenian Hamster Anti-Mouse CD120b Antibody(Clone TR75-54.7), AF/LE Purified

Cat NoBIOS-2290F
Conjugate
Type流式抗体
CloneTR75-54.7
SourceMouse
TagAF/LE Purified
Size1 mg
ApplicationFCM
FormatLiquid
Purity>90%
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS; pH 7.4.
StorageStore at -20 degree for long term.
SynonymsTumor necrosis factor receptor superfamily member 1B;Tnfrsf1b;Tumor necrosis factor receptor 2;TNF-R2;TNF-RII;TNFR-II;p75;p80 TNF-alpha receptor;CD120b
PurificationSDS-PAGE
MolecularWeight
Description
BackgroundCD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.
We can provide a variety of products such as diagnostic proteins; target proteins; cytokines; etc.
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