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Rat Anti-Mouse CD45.2 Antibody(Clone 104.2), AF/LE Purified

Cat NoBIOS-2196F
Conjugate
Type流式抗体
SourceRat
TagAF/LE Purified
Size1 mg
ApplicationFCM
ApplicationNoteEach lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
FormatLiquid
Purity>90%
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS; pH 7.4.
StorageStore at -20 degree for long term.
SynonymsLy-5.2;LCA
PurificationSDS-PAGE
MolecularWeight
Description
BackgroundCD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
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