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Armenian Hamster Anti-Mouse TCR γ/δ Antibody(Clone UC7-13D5), AF/LE Purified

Cat NoBIOS-2080F
Conjugate
Type流式抗体
CloneUC7-13D5
SourceMouse
TagAF/LE Purified
Size1 mg
ApplicationFCM
FormatLiquid
Purity>90%
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS; pH 7.4.
StorageStore at -20 degree for long term.
SynonymsArmenian Hamster IgG
PurificationSDS-PAGE
MolecularWeight
Description
BackgroundT cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR γ/δ associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR γ/δ have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-γ/δ-bearing T cells in vitro, and to deplete peripheral TCR-γ/δ-bearing T cells in vivo.
We can provide a variety of products such as diagnostic proteins; target proteins; cytokines; etc.
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