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Cat No | BIOS-0214F |
Conjugate | |
Type | 流式抗体 |
Clone | FD441.8 |
Source | Rat |
Tag | Biotin |
Size | 1 mg |
Application | FCM |
ApplicationNote | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Format | Liquid |
Purity | >90% |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS; pH 7.4. |
Storage | Store at -20 degree for long term. |
Synonyms | Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a |
Purification | SDS-PAGE |
MolecularWeight | |
Description | |
Background | CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). |