Biotyscience Inc
Tel 400-669-8850
E-mail info@biotyscience.com
QQ 499854788
82458988
Cat No | BIOC1213 |
Conjugate | |
Type | Carrier Material |
Source | N/A |
Size | 1 g |
Application | |
Format | Powder |
Buffer | 可溶于氯仿、二氯甲烷、丙酮、DMF、DMSO等有机溶剂 |
Storage | Store at 2-8℃. Keep away from light. |
Synonyms | 马来酰亚胺-聚乙二醇-聚乳酸;PLA-PEG-MAL;mal pla |
Purification | ≥95% |
MolecularWeight | 2000/3400/5000 |
Description | |
Background | Poly(L-lactide)-PEG-Maleimide (PLLA-PEG-MAL) is a functional amphiphilic block copolymer to prepare targeted micelles or nanoparticles. Maleimide can conjugate with thiol, SH, sulfhydryl or mercapto group to form a disulfide bond. Block copolymer micelles are widely used in drug delivery applications. PEG-PLA is a biodegradable polymeric micelle which is used as carriers for hydrophobic drugs like paclitaxel. PEG is the hydrophilic part and PLA is the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded. |