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HO-PEG-Mal

Cat NoBIOC1143
Conjugate
TypeCarrier Material
SourceN/A
Size1 g
Application
FormatPowder
StorageStore at 2-8℃. Keep away from light.
SynonymsHO-PEG-Mal;羟基-聚乙二醇-马来酰亚胺
Purification≥95%
MolecularWeight2000/3400/5000
Description
BackgroundHO-PEG-Mal, MW 2,000 is a thiol reactive PEG polymer. The PEG is water soluble and hydroxyl moiety allows further modification with other reactive group.HO-PEG-mal (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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