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Cat No | BPA-17019 |
Conjugate | |
Type | Phosphorylated Antibody |
Source | Rabbit |
Size | 50 uL |
Application | WB |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Species | Mouse |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Synonyms | TYK2;IMD35;JTK1 |
Purification | Affinity purification |
MolecularWeight | 134KDa |
Description | |
Background | This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. |