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Rabbit Anti-LMNA Polyclonal Antibody

Cat NoBSPA-2195
Conjugate
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; WB; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsLMNA;lamin A/C;FPL;IDC;LFP;CDDC;EMD2;FPLD;HGPS;LDP1;LMN1;LMNC;PRO1;CDCD1;CMD1A;FPLD2;LMNL1;CMT2B1;LGMD1B;lamin;70 kDa lamin;prelamin-A/C;lamin A/C-like 1;renal carcinoma antigen NY-REN-32
Purification
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
BackgroundLamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells , leading to mitotic failure, genomic instability, and premature senescence.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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