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Cat No | BSPA-0978 |
Conjugate | |
Type | Polyclonal Antibody |
Source | Rabbit |
Size | 1 mg |
Application | ELISA; WB; IHC |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Species | Human |
Storage | Store at -20 degree. Avoid repeted freeze/thaw cycl. |
Synonyms | ARHGDIB;Rho GDP dissociation inhibitor beta;D4;GDIA2;GDID4;LYGDI;Ly-GDI;RAP1GN1;RhoGDI2 |
Purification | |
Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
MolecularWeight | |
Description | |
Background | Members of the Rho protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins , guanine nucleotide-releasing factors , and GDP-dissociation inhibitors . The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases. |