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Cat No | BQSB-003-G |
Conjugate | |
Type | 天然蛋白 |
Source | Human |
Tag | N/A |
Size | 1 mg |
Application | ELISA; TIA; LF; CLIA |
Format | Colorless transparent liquid. |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 0.01 mol/L PBS, pH 7.4. |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | 补体C3;Complement C3;Complement C-3;back top;C3;CPAMD1;ASP |
Purification | Protein A |
MolecularWeight | |
Description | |
Background | Compstatin is an effective inhibitor of the activation of complement component C3 and thus blocks a central and essential step in the complement cascade. The specific binding site on C3, the configuration in the bound form, and the exact mode of action of compstatin are unknown. The crystal structure of compstatin in complex with C3c reveals that the compstatin-binding site is formed by the macroglobulin (MG) domains 4 and 5. |