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Cat No | BIOP3624 |
Conjugate | |
Type | 药物靶点 |
Source | E. coli |
Size | 10 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 20mM PB,150mM NaCl,pH 7.4. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | Alpha-Synuclein;Non-A Beta Component of AD Amyloid;Non-A4 Component of AmyloidPrecursor;NACP;SNCA;NACP;PARK1 |
Purification | > 95% by SDS-PAGE. |
MolecularWeight | |
Description | aa 1-140 |
Background | Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but alsoexpressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D andhistones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatorycomponent of vesicular transport in neuronal cells. It has been suggested that SNCA is related to thepathogenesis of Parkinsons Disease and neurodegenerative disorders. Defects in SNCA will lead to DementiaLewy Body (DLB). |