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Cat No | BIOP3596 |
Conjugate | |
Type | 药物靶点 |
Source | HEK293 |
Tag | His |
Size | 20 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS, pH 7.4. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | CD29;FNRB;GPIIA;MDF2;MSK12;VLA-BETA;VLAB |
Purification | > 90% by SDS-PAGE. |
MolecularWeight | |
Description | aa 1-728 |
Background | Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling). Integrin beta-1 can help to regulate cell proliferation, cytoskeletal reorganization, and gene expression. Research studies have integrin beta-1 integrin in various activities including embryonic development, blood vessel, skin, bone, and muscle formation, as well as tumor metastasis and angiogenesis. |