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Cat No | BIOP3495 |
Conjugate | |
Type | 药物靶点 |
Source | HEK293 |
Tag | Fc-His |
Size | 20 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS, pH 7.4. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | CD279;hPD-1;hPD-l;hSLE1;PD-1;PD1;SLEB2 |
Purification | > 97% by SDS-PAGE. |
MolecularWeight | |
Description | aa 25-168 |
Background | This protein is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. |