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Cat No | BIOP3277 |
Conjugate | |
Type | 细胞培养 |
Source | E. coli |
Size | 20 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 30 % CAN, 0.1 % TFA, pH 2.9. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | BDA2;BDA2A;BMP-2;BMP2A;BMP-2 |
Purification | > 95 % by SDS-PAGE. |
MolecularWeight | |
Description | aa 283-396 |
Background | This protein is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. |