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Recombinant Human SIRPG/SIRPB2 Protein(aa 29-360), Fc

Cat NoBIOP2910
Conjugate
Type生物标志物
SourceHEK293
TagFc
Size10 ug
ApplicationImmunogen
FormatLyophilized
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS, pH 7.4.
SpeciesHuman
StorageStore at –20 degree. Avoid repeated freeze/thaw cycles.
SynonymsSignal-Regulatory Protein Gamma;SIRP-Gamma;CD172 Antigen-Like Family Member B;Signal-Fegulatory Protein Beta-2;SIRP-b2;SIRP-Beta-2;CD172g;SIRPG;SIRPB2
Purification> 95% by SDS-PAGE.
MolecularWeight
Descriptionaa 29-360
BackgroundSignal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and alsobelongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain,heart, lung, pancreas, kidney, placenta, and skeletal muscle. SIRPG is an immunoglobulin-like cell surfacereceptor. On binding with CD47, SIRPG mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.SIRPG as receptor-type transmembrane glycoproteins is involved in the negative regulation of receptortyrosine kinase-coupled signaling processes.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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