Biotyscience Inc
Tel 400-669-8850
E-mail info@biotyscience.com
QQ 499854788
82458988
Cat No | BIOP2421 |
Conjugate | |
Type | 其他蛋白 |
Source | E. coli |
Tag | GST |
Size | 20 ug |
Application | Immunogen |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 50mM Tris,150mM NaCl,0.1mM EDTA,0.25mM DTT,0.1mM AEBSF,25%glycerol,10mM GSH,pH 8.0. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | ERK;ERK-2;ERK2;ERT1;MAPK2;p38;p40;p41;p41mapk;p42-MAPK;P42MAPK;PRKM1;PRKM2 |
Purification | > 70% by SDS-PAGE. |
MolecularWeight | |
Description | aa 1-360 |
Background | ERK2 is a protein serine/threonine kinase, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. |