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Cat No | BIOP2253 |
Conjugate | |
Type | 免疫检查点 |
Source | HEK293 |
Tag | Fc |
Size | 20 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS, pH 7.4. |
Species | Mouse |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | CD86;B7-2;B70;CD28LG2;LAB72;MGC34413 |
Purification | > 97% by SDS-PAGE. |
MolecularWeight | |
Description | aa 24-245 |
Background | CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. CD86 is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. |