中文English Call: 400-669-8850 | E-mail: info@biotyscience.com

重组蛋白

当前位置:首页 >>产品中心 >>蛋白产品 >>重组蛋白

Content

Contact us

Biotyscience Inc

Tel 400-669-8850

E-mail info@biotyscience.com

QQ  499854788

       82458988


Recombinant Human IL23R Protein, hFc

Cat NoBIOP2170
Conjugate
Type白介素
SourceHEK293
TaghFc
Size20 ug
ApplicationImmunogen
FormatLyophilized
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS, pH 7.4.
SpeciesHuman
StorageStore at –20 degree. Avoid repeated freeze/thaw cycles.
SynonymsIL-23 R;IL-23 Receptor
Purification> 95% by SDS-PAGE.
MolecularWeight
Description
BackgroundIL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isoform 1 is specifically expressed in NK cells. IL23R associates with IL12RB1 to form the interleukin-23 receptor. It binds IL23 and mediates T-cells, NK cells, and possibly certain macrophage/myeloid cell stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Genetic variations in IL23R are associated with inflammatory bowel disease type 17 (IBD17). IBD17 is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. Genetic variations in IL23R also can cause susceptibility to psoriasis type 7.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
咨询热线:
客服:400-669-8850 产品:177-3110-0244 服务:136-8125-6816
在线客服:
产品咨询-1点击这里给我发消息QQ交谈
服务咨询-2点击这里给我发消息QQ交谈
微信二维码:
公司官网: biotyscience.com