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Cat No | BIOP2121 |
Conjugate | |
Type | 白介素 |
Source | Mammalian |
Tag | His |
Size | 10 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS, pH 7.4. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | Interleukin-18 receptor accessory protein (IL18RAP);Accessory protein-like;CD218 antigen-like family member B;CDw218b;IL-1R accessory protein-like;Interleukin-1 receptor 7;Interleukin-18 receptor accessory protein-like;Interleukin-18 receptor beta£ |
Purification | > 95% by SDS-PAGE. |
MolecularWeight | |
Description | aa 20-356 |
Background | This protein is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohns disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. |