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Cat No | BIOP2109 |
Conjugate | |
Type | 白介素 |
Source | HEK293 |
Tag | His |
Size | 10 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 20mM PB, 150mM NaCl, pH 7.4. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | Interleukin-20 Receptor Subunit Alpha;IL-20 Receptor Subunit Alpha;IL-20R-Alpha;IL-20RA;Cytokine Receptor Class-II Member 8;Cytokine Receptor Family 2 Member 8;CRF2-8;IL-20R1;ZcytoR7;IL20RA |
Purification | > 95% by SDS-PAGE. |
MolecularWeight | |
Description | aa 30-250 |
Background | Interleukin-20 Receptor Subunit α (IL20RA) is a single-pass type I membrane protein that is a member of thetype II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29amino acid signal peptide, a 221 amino acid extracellular domain with two fibronectin type-III domains, a 24amino acid transmembrane region, and a 279 amino acid intracellular domain. IL20RA is widely expressed withhighest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB, andthe complex serves as a receptor for IL19, IL20 and IL24. IL20RA also forms a heterodimer with the unique andspecific receptor IL10RB and functions as the receptor for IL26. |