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Recombinant Human IL-16 Protein(aa 2-130), His

Cat NoBIOP2059
Conjugate
Type白介素
SourceE. coli
TagHis
Size10 ug
ApplicationImmunogen
FormatLyophilized
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in 20mM Tris, 150mM NaCl, pH 8.0.
SpeciesHuman
StorageStore at –20 degree. Avoid repeated freeze/thaw cycles.
SynonymsLCF;NIL16;prIL-16;PRIL16
Purification> 97% by SDS-PAGE.
MolecularWeight
Descriptionaa 2-130
BackgroundThe protein is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The biological activities ascribed to IL-16 are reported to be dependent on the cell surface expression of CD4, suggesting that IL-16 is a CD4 ligand. Besides its chemotactic properties, IL-16 has also been shown to suppress HIV-1 replication in vitro. Recombinant E. coli-derived IL-16 produced at is present mostly as a monomer, exhibits chemotactic activity for lymphocytes at high concentrations, lacks chemotactic activites for monocytes, and binds the extracellular domain of CD4 with low affinity.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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