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Recombinant Mouse EpCAM/TROP1/CD326/Epithelial cell adhesion molecule/Tumor-associated calcium signal transducer 1 Protein(aa 24-266), Fc

Cat NoBIOP1823
Conjugate
TypeCAR-T相关
SourceHEK293
TagFc
Size10 ug
ApplicationImmunogen
FormatLyophilized
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS, pH 7.4.
SpeciesMouse
StorageStore at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms17-1A;323/A3;ACSTD1;CD326;EGP-2;EGP314;EGP40;EpCAM;MOC31;TACST-1;TACSTD1;TROP1
Purification> 95% by SDS-PAGE.
MolecularWeight
Descriptionaa 24-266
BackgroundEpithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its ’ monomer subunit structureinteracts with phosphorylated CLDN7. Ep-CAM may act as a physical homophilic interaction molecule betweenintestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providingimmunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cellsproliferation and differentiation. It also up-regulates the expression of FABP5, MYC and cyclins A and E. Thepost-translational modification glycosylation at Asn-198 is crucial for protein stability.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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