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Cat No | ADY-85 |
Conjugate | |
Type | 病毒相关蛋白 |
Source | E.coli |
Tag | His |
Size | 1 mg |
Application | ELISA |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Reconstituted protein solution should be stored at ≤ -20°C. Stable for at least 24 months when stored as instructed. |
Synonyms | Insulin-Like Growth Factor I;IGF-I;Mechano Growth Factor;MGF;Somatomedin-C;IGF1;IBP1 |
Purification | Protein A |
MolecularWeight | 7.3kDa |
Description | |
Background | Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone. |