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| Cat No | BXXB-379 |
| Conjugate | |
| Type | 血清及免疫球蛋白 |
| Source | N/A |
| Size | 1 mg |
| Application | Immunology |
| Format | Liquid |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Buffer | Supplied in PBS. |
| Storage | Store at -20 degree for long time. Avoid repeated freeze/thaw cycles. |
| Synonyms | Human Fibrinogen;Fibrinogen;Fbg;血纤维蛋白原 |
| Purification | Protein A |
| MolecularWeight | |
| Description | |
| Background | This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. |