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Cat No | BIOC1190 |
Conjugate | |
Type | Carrier Material |
Source | N/A |
Size | 1 g |
Application | |
Format | Powder |
Buffer | 溶于常规水溶液以及大多数有机溶剂 |
Storage | Store at 2-8℃. Keep away from light. |
Synonyms | PLGA-PEG-NH2;PLGA聚(D;L-丙交酯-co-乙交酯)-PEG-胺 |
Purification | ≥95% |
MolecularWeight | 2000/3400/5000 |
Description | |
Background | PLGA(5k)-PEG(5k)-NH2 is an amino terminated amphiphile polymer. The terminal amine can react with NHS ester at pH 7-9 to form a stable amide linkage. Upon dispersion in water, the polymer self-assembles to form micelles with poly(lactide-co-glycolide) (PLGA) core and PEG shell. The core can be used as hydrophobic drugs reservoir while the shell can protect against enzymatic/hydrolysis degradation. The polymer is biodegradable and can be used for sustained release drug delivery. |