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PLGA-PEG-NH2

Cat NoBIOC1190
Conjugate
TypeCarrier Material
SourceN/A
Size1 g
Application
FormatPowder
Buffer溶于常规水溶液以及大多数有机溶剂
StorageStore at 2-8℃. Keep away from light.
SynonymsPLGA-PEG-NH2;PLGA聚(D;L-丙交酯-co-乙交酯)-PEG-胺
Purification≥95%
MolecularWeight2000/3400/5000
Description
BackgroundPLGA(5k)-PEG(5k)-NH2 is an amino terminated amphiphile polymer. The terminal amine can react with NHS ester at pH 7-9 to form a stable amide linkage. Upon dispersion in water, the polymer self-assembles to form micelles with poly(lactide-co-glycolide) (PLGA) core and PEG shell. The core can be used as hydrophobic drugs reservoir while the shell can protect against enzymatic/hydrolysis degradation. The polymer is biodegradable and can be used for sustained release drug delivery.
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