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Dextran

Cat NoBIOC1174
Conjugate
TypeCarrier Material
SourceN/A
Size1 g
Application
FormatPowder
StorageStore at 2-8℃. Keep away from light.
Synonyms葡萄糖-NH2;葡萄糖-氨基
Purification≥95%
MolecularWeight2000/3400/5000
Description
BackgroundDextran is a heterogeneous polysaccharide synthesized by the action of the bacteriumLeuconostoc mesenteroides on sucrose. Two commercially available forms of dextran are available, dextran 40 and dextran 70, named according to the average molecular weights of the polysaccharides in the preparations. Dextrans were initially used as colloids for fluid resuscitation; however, problems with potential anaphylactic reactions and effects on the coagulation system led to a general abandonment of the use of dextrans in this setting. It is their effects on coagulation that have been exploited in microvascular surgery. Dextrans appear to interfere with the formation of fibrin networks, increase the degradation of fibrin, decrease von Willebrand factor and factor VII, and expand intravascular volume.
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