中文English Call: 400-669-8850 | E-mail: info@biotyscience.com

修饰性抗体

当前位置:首页 >>产品中心 >>抗体产品 >>一抗 >>修饰性抗体

Contact us

Biotyscience Inc

Tel 400-669-8850

E-mail info@biotyscience.com

QQ  499854788

       82458988


Rabbit anti-Human Phospho-Androgen Receptor-S650 Polyclonal Antibody

Cat NoBPA-17086
Conjugate
TypePhosphorylated Antibody
SourceRabbit
Size50 uL
ApplicationWB; IF
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS with 0.02% sodium azide,50% glycerol,pH7.3.
SpeciesHuman
StorageStore at -20℃. Avoid freeze / thaw cycles.
SynonymsAIS;AR8;DHTR;HUMARA;HYSP1;KD;NR3C4;SBMA;SMAX1;TFM;AR
PurificationAffinity purification
MolecularWeight
Description
BackgroundThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
客服:
400-669-8850
产品:
177-3110-0244
服务:
136-8125-6816
QQ 在线咨询

微信二维码
电子邮箱
info@biotyscience.com