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Rabbit anti-Human Phospho-eIF4EBP1-T36 Polyclonal Antibody

Cat NoBPA-17074
Conjugate
TypePhosphorylated Antibody
SourceRabbit
Size50 uL
ApplicationWB; IHC; IF
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS with 0.02% sodium azide,50% glycerol,pH7.3.
SpeciesHuman
StorageStore at -20℃. Avoid freeze / thaw cycles.
Synonyms4E-BP1;4EBP1;BP-1;PHAS-I;EIF4EBP1
PurificationAffinity purification
MolecularWeight20kDa
Description
BackgroundThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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