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Cat No | BSPA-0701 |
Conjugate | |
Type | Polyclonal Antibody |
Source | Rabbit |
Size | 1 mg |
Application | ELISA; IHC |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Species | Human |
Storage | Store at -20 degree. Avoid repeted freeze/thaw cycl. |
Synonyms | argonaute 1, RISC catalytic component;Q99;EIF2C;hAgo1;EIF2C1;GERP95 |
Purification | |
Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
MolecularWeight | |
Description | |
Background | This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference and RNA silencing. This protein binds to microRNAs or small interfering RNAs and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing of promoter regions that are complementary to bound short antigene RNAs , as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. |