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Cat No | BSPA-2327 |
Conjugate | |
Type | Polyclonal Antibody |
Source | Rabbit |
Size | 1 mg |
Application | ELISA; WB; IHC |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Species | Human |
Storage | Store at -20 degree. Avoid repeted freeze/thaw cycl. |
Synonyms | NDUFS1;NADH dehydrogenase Fe-S protein 1, 75kDa;NADH dehydrogenase Fe S protein 1;NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial;CI 75k;complex I 75kDa subunit;NADH ubiquinone oxidoreductase 75 kDa subunit;mitochondrial;complex I, mitochondrial respiratory chain, 75-kD subunit;mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit |
Purification | |
Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
MolecularWeight | |
Description | |
Background | The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. |