Biotyscience Inc
Tel 400-669-8850
E-mail info@biotyscience.com
QQ 499854788
82458988
Cat No | BSPA-2022 |
Conjugate | |
Type | Polyclonal Antibody |
Source | Rabbit |
Size | 1 mg |
Application | ELISA; IHC |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Species | Human |
Storage | Store at -20 degree. Avoid repeted freeze/thaw cycl. |
Synonyms | HSPB8;heat shock 22kDa protein 8;H11;HMN2;CMT2L;DHMN2;E2IG1;HMN2A;HSP22;heat shock protein beta-8;protein kinase H11;alpha-crystallin C chain;E2-induced gene 1 protein;heat shock 27kDa protein 8;small stress protein-like protein HSP22 |
Purification | |
Note | Tis product l is eeze eezeleezeegrrch useeze ly, no useeze huma, apeut agnost apcal. |
MolecularWeight | |
Description | |
Background | The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008] |