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Cat No | BSPA-1254 |
Conjugate | |
Type | Polyclonal Antibody |
Source | Rabbit |
Size | 1 mg |
Application | ELISA; WB; IHC |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Species | Human |
Storage | Store at -20 degree. Avoid repeted freeze/thaw cycl. |
Synonyms | BIRC7;baculoviral IAP repeat containing 7;KIAP;LIVIN;MLIAP;RNF50;ML-IAP;baculoviral IAP repeat-containing protein 7;RING finger protein 50;livin inhibitor of apoptosis;kidney inhibitor of apoptosis protein;melanoma inhibitor of apoptosis protein |
Purification | |
Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
MolecularWeight | |
Description | |
Background | This gene encodes a member of the inhibitor of apoptosis protein family, and contains a single copy of a baculovirus IAP repeat as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants |