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Cat No | BSPA-0490 |
Conjugate | |
Type | Polyclonal Antibody |
Source | Rabbit |
Size | 1 mg |
Application | ELISA; IHC |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Species | Human |
Storage | Store at -20 degree. Avoid repeted freeze/thaw cycl. |
Synonyms | ABHD12;abhydrolase domain containing 12;C20orf22, chromosome 20 open reading frame 22;monoacylglycerol lipase ABHD12;ABHD12A;BEM46L2;dJ965G21.2;DKFZP434P106;2-arachidonoylglycerol hydrolase;abhydrolase domain-containing protein 12;PHARC;C20orf22;DKFZp434P106 |
Purification | |
Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
MolecularWeight | |
Description | |
Background | This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol , the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC , resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |