中文English Call: 400-669-8850 | E-mail: info@biotyscience.com

单克隆抗体

当前位置:首页 >>产品中心 >>抗体产品 >>一抗 >>单克隆抗体

Contact us

Biotyscience Inc

Tel 400-669-8850

E-mail info@biotyscience.com

QQ  499854788

       82458988


Rabbit anti-Human DDB1 Monoclonal Antibody

Cat NoBMA-1420
Conjugate
Type重组兔多抗
SourceRabbit
Size50 uL
ApplicationImmunogen
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
SpeciesHuman
StorageStore at -20℃. Avoid freeze / thaw cycles.
SynonymsDDBA;UV-DDB1;XAP1;XPCE;XPE;XPE-BF
PurificationAffinity purification
MolecularWeight127KDa
Description
BackgroundThe protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
客服:
400-669-8850
产品:
177-3110-0244
服务:
136-8125-6816
QQ 在线咨询

微信二维码
电子邮箱
info@biotyscience.com