中文English Call: 400-669-8850 | E-mail: info@biotyscience.com

单克隆抗体

当前位置:首页 >>产品中心 >>抗体产品 >>一抗 >>单克隆抗体

Content

Contact us

Biotyscience Inc

Tel 400-669-8850

E-mail info@biotyscience.com

QQ  499854788

       82458988


Rabbit anti-Mouse TPPP/p25 Monoclonal Antibody

Cat NoBMA-1346
Conjugate
Type重组兔多抗
SourceRabbit
Size50 uL
ApplicationImmunogen
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
SpeciesMouse
StorageStore at -20℃. Avoid freeze / thaw cycles.
SynonymsTPPP/p25;TPPP1;p24;p25;p25alpha
PurificationAffinity purification
MolecularWeight26KDa
Description
BackgroundRegulator of microtubule dynamics that plays a key role in myelination by promoting elongation of the myelin sheath. Acts as a microtubule nucleation factor in oligodendrocytes: specifically localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, and promotes microtubule nucleation, an important step for elongation of the myelin sheath. Required for both uniform polarized growth of distal microtubules as well as directing the branching of proximal processes. Shows magnesium-dependent GTPase activity; the role of the GTPase activity is unclear. In addition to microtubule nucleation activity, also involved in microtubule bundling and stabilization of existing microtubules, thereby maintaining the integrity of the microtubule network. Regulates microtubule dynamics by promoting tubulin acetylation: acts by inhibiting the tubulin deacetylase activity of HDAC6. Also regulates cell migration: phosphorylation by ROCK1 inhibits interaction with HDAC6, resulting in decreased acetylation of tubulin and increased cell motility. Plays a role in cell proliferation by regulating the G1/S-phase transition. Involved in astral microtubule organization and mitotic spindle orientation during early stage of mitosis; this process is regulated by phosphorylation by LIMK2.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
咨询热线:
客服:400-669-8850 产品:177-3110-0244 服务:136-8125-6816
在线客服:
产品咨询-1点击这里给我发消息QQ交谈
服务咨询-2点击这里给我发消息QQ交谈
微信二维码:
公司官网: biotyscience.com