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Mouse anti-Galectin-3 Monoclonal Antibodiy, clone T31

Cat NoBMM-049
Conjugate
Type抗体对
CloneT31
SourceMouse
Size1mg
ApplicationLF; ELISA
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS with 6% Mannitol, pH7.4.
StorageStore at -20 degree for long time. Avoid repeated freeze/thaw cycles.
Synonyms35 kDa lectin;CBP35;GAL3;GALBP;Galectin-3;GALIG;L-31;Lectin L-29;LGALS2;LGALS3;MAC2
PurificationProtein A
MolecularWeight
Description
BackgroundGalectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides. Galectin-3, a 31-kDa member of the β-galactoside-binding proteins, contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell, being present on the cell surface or in the extracellular space. Galectin-3 is involved in various biological processes including cell growth, adhesion, differentiation, apoptosis, angiogenesis, immune response, neoplastic transformation and metastasis. Elevated serum galectin-3 levels have been reported in patients with breast, gastrointestinal, lung, or ovarian cancer, melanoma, and non-Hodgkin's lymphoma.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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